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tert-Butyl 3-(4-aminophenyl)pyrrolidine-1-carboxylate

  • CAS No. 908334-28-1

  • Cat. No. CS-W007192
  • Molecule weight262.35
  • Purity≥97%
  • MDL No.MFCD08751372

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3-(4-aminophenyl)pyrrolidine-1-carboxylate|CS-W007192

Structure of 908334-28-1

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General Information

  • CAS No. 908334-28-1
  • Cat. No. CS-W007192
  • Purity ≥97%
  • MDL No. MFCD08751372
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₂N₂O₂
  • Molecular Weight 262.35
  • Synonym(s) 3-(4-Amino-phenyl)-pyrrolidine-1-carboxylic acid tert-butyl ester
  • SMILES O=C(N1CC(C2=CC=C(N)C=C2)CC1)OC(C)(C)C

Synthesis

  • Route1
    • null|null
      1428760-69-3
    • ~35%
    • tert-Butyl 3-(4-aminophenyl)pyrrolidine-1-carboxylate|CS-W007192
      908334-28-1

    References

    • AFRAXIS, INC.; CAMPBELL, David; DURÓN, Sergio, G. Patent: WO2013/43232 A2, 2013 ; Location in patent: Paragraph 00530 ; WO 2013/043232 A2
  • Route2

    References

    • CANCER THERAPEUTICS CRC PTY LIMITED; HOLMES, Ian, Peter; BERGMAN, Ylva; LUNNISS, Gillian Elizabeth; NIKAC, Marica; CHOI, Neil; HEMLEY, Catherine Fae; WALKER, Scott Raymond; FOITZIK, Richard Charles; GANAME, Danny; LESSENE, Romina Patent: WO2012/110773 A1, 2012 ; Location in patent: Page/Page column 149; 150; 151 ; WO 2012/110773 A1
  • Route3

    References

    • CANCER THERAPEUTICS CRC PTY LTD; DEVLIN, Mark Graeme; STREET, Ian Philip; TONG, Warwick Bonner Patent: WO2014/27199 A1, 2014 ; Location in patent: Page/Page column 152-153 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08,GHS09
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301+H311+H331-H319-H334-H351-H410
Precautionary Statements : P261-P273-P280

Quality Control

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   2.9932
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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