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Structure of 91183-17-4
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5-(Benzyloxy)-2,4-dichloropyrimidine features a benzyloxy substituent at the 5-position, enhancing solubility and stability in organic synthesis. The electron-deficient pyrimidine core facilitates nucleophilic substitution reactions. This compound serves as a key intermediate in the construction of bioactive heterocycles and kinase inhibitors under standard conditions.
5-(Benzyloxy)-2,4-dichloropyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The benzyloxy group offers orthogonal stability under standard reaction conditions while allowing selective deprotection when required. Its dichloropyrimidine core facilitates nucleophilic substitution at C5, supporting the construction of diverse heterocyclic scaffolds relevant to kinase inhibitors and antiviral agents. The compound exhibits excellent bench stability and compatibility with common purification methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: