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CS-W001157 4
Total: USD 88.00

H-Met-OtBu.HCl

  • CAS No. 91183-71-0

  • Cat. No. CS-W010278
  • Purity≥97%
  • MDL No.MFCD00038896

*For research and further manufacturing use only, not for direct human use.

H-Met-OtBu.HCl|CS-W010278

Structure of 91183-71-0

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General Information

  • CAS No. 91183-71-0
  • Cat. No. CS-W010278
  • Purity ≥97%
  • MDL No. MFCD00038896
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₀ClNO₂S
  • Molecular Weight 241.78
  • Synonym(s) None
  • SMILES N[C@@H](CCSC)C(OC(C)(C)C)=O.[H]Cl

Description

H-Met-OtBu·HCl delivers a stable, bench-ready sulfide handle for late-stage functionalization. The protected thioether moiety resists oxidation and integrates cleanly into peptide backbones or small-molecule scaffolds under standard coupling conditions. This moisture-tolerant reagent enables efficient incorporation of methionine analogs in synthetic workflows.

Application

H-Met-OtBu·HCl serves as a reliable building block for peptide synthesis, offering a stable, bench-ready form of methionine with orthogonal protection. The tert-butyl ester facilitates straightforward deprotection under mild acidic conditions, while the HCl salt enhances solubility and handling. It functions effectively in standard coupling protocols, enabling efficient incorporation into peptide chains with minimal racemization.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.8303
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   4

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