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Structure of 912369-50-7
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1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine features a boronate ester handle enabling robust Suzuki-Miyaura coupling under mild conditions. The piperazine moiety provides solubility and polarity, while the tetramethyl-substituted dioxaborolane enhances stability and shelf life. This compound integrates efficiently into complex molecular architectures during medicinal chemistry campaigns.
1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. Its piperazine moiety offers enhanced solubility and metabolic stability, while the tetramethylboronate group enables robust coupling under mild conditions. The compound exhibits excellent bench stability, facilitates straightforward purification, and functions reliably in the synthesis of biologically relevant heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: