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Structure of 912771-28-9
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1,3-Dimethylpyrrolidine-3-carboxylic acid features a sterically hindered pyrrolidine core with dual methyl substitutions that enhance metabolic stability and modulate lipophilicity. This conformationally restricted scaffold integrates readily into bioactive molecules, offering improved membrane permeability and resistance to enzymatic degradation in medicinal chemistry applications.
1,3-Dimethylpyrrolidine-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide mimetics. Its constrained pyrrolidine core offers favorable conformational stability, while the carboxylic acid functionality facilitates direct coupling or derivatization. The N-methyl and C3-methyl groups enhance metabolic stability and lipophilicity, making it a practical scaffold for optimizing pharmacokinetic properties in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: