(R)-2-(1-(tert-Butoxycarbonyl)piperidin-3-yl)acetic acid

Name: (R)-2-(1-(tert-Butoxycarbonyl)piperidin-3-yl)acetic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 912940-89-7
Cat. No. CS-0028283
Purity≥95%
MDL No.MFCD03094721

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-2-(1-(tert-Butoxycarbonyl)piperidin-3-yl)acetic acid|CS-0028283

Structure of 912940-89-7

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Description

This chiral building block features a protected piperidine moiety integrated with a carboxylic acid side chain, enabling direct incorporation into peptide and peptidomimetic architectures. The (R)-stereochemistry at the C3 position ensures precise spatial orientation in synthetic sequences. The tert-butoxycarbonyl group provides stable protection under standard conditions, simplifying downstream deprotection and functionalization workflows.

Application

(R)-2-(1-(tert-Butoxycarbonyl)piperidin-3-yl)acetic acid serves as a versatile chiral building block for the synthesis of bioactive molecules, particularly in medicinal chemistry. The protected piperidine moiety enables efficient functionalization and orthogonal deprotection, while the acetic acid side chain facilitates conjugation or further derivatization. Bench-stable and readily purified by standard chromatographic methods, it functions reliably in peptide coupling, heterocycle formation, and scaffold elaboration workflows.

General Information

CAS No. 912940-89-7
Cat. No. CS-0028283
Purity ≥95%
MDL No. MFCD03094721
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₂₁NO₄
Molecular Weight None
Synonym(s) None
SMILES CC(C)(C)OC(N1C[C@H](CCC1)CC(O)=O)=O

Computational Chemistry Data

TPSA 66.84
LogP 2.1082
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-2-(1-(tert-Butoxycarbonyl)piperidin-3-yl)acetic acid

CAS No. 912940-89-7

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