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Structure of 913574-93-3
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This difluorinated acetic acid derivative features a 4-bromophenyl substituent that imparts enhanced lipophilicity and metabolic stability. The electron-withdrawing fluorine atoms amplify acidity while maintaining bench-stable handling properties. This structural motif serves as a key building block in the synthesis of bioactive pharmaceutical intermediates, particularly those requiring halogenated aromatic frameworks for targeted receptor interactions.
2-(4-Bromophenyl)-2,2-difluoroacetic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated aryl motifs found in bioactive molecules. Its difluoromethyl group imparts metabolic stability and enhanced lipophilicity, while the bromophenyl moiety facilitates downstream cross-coupling reactions. The compound exhibits bench stability and is compatible with standard purification techniques, making it well-suited for use in iterative synthesis campaigns targeting complex heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: