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Structure of 914950-66-6
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Methyl 6-ethynylpicolinate is a synthetically valuable pyridine derivative featuring a terminal alkyne group at the 6-position. This functionality enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and materials assembly. The ester moiety enhances solubility in organic solvents while maintaining stability under standard bench conditions.
Methyl 6-ethynylpicolinate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted pyridine scaffolds via transition-metal-catalyzed coupling reactions. The terminal alkyne moiety facilitates reliable Sonogashira and Glaser-type couplings, while the ester group offers orthogonal reactivity for further functionalization. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: