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Structure of 915087-26-2
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4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide features a sterically hindered cyclobutyl amine linked to an electron-deficient aryl scaffold, delivering enhanced metabolic stability. The para-fluoro and methyl substituents optimize target engagement, while the nitrile group enables downstream derivatization. This compound serves as a robust pharmacophore in kinase inhibitor design.
4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide serves as a versatile building block in medicinal chemistry, enabling the construction of diverse heterocyclic scaffolds through nucleophilic addition to the nitrile group. The molecule exhibits bench-stable handling, good solubility in common organic solvents, and tolerance to a range of functional groups, facilitating straightforward purification and integration into multi-step synthesis workflows. Its fluorinated aryl core enhances metabolic stability and membrane permeability, making it a practical intermediate for targeted compound libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: