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Structure of 915140-06-6
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2-(Hydroxymethyl)isonicotinic acid features a pyridine ring bearing both carboxylic acid and hydroxymethyl functional groups at the 2- and 6-positions, respectively. This arrangement enables direct incorporation into bioconjugation workflows, where the hydroxyl group serves as a site for derivatization or metal chelation. The molecule exhibits enhanced solubility in aqueous systems compared to related aromatic acids, facilitating use in biological assay development and peptide synthesis.
2-(Hydroxymethyl)isonicotinic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates. Its pyridine core enables facile derivatization, while the pendant hydroxymethyl group offers direct access to aldehyde or carboxylic acid functionalities via oxidation. The molecule exhibits good bench stability and compatibility with standard coupling and protection protocols, facilitating integration into multistep synthetic sequences for API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: