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Structure of 915230-46-5
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5-(Trifluoromethyl)-1H-imidazole-2-carboxylic acid features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the carboxylic acid moiety enables direct conjugation or derivatization. This combination delivers a robust scaffold for medicinal chemistry applications, particularly in developing bioactive heterocycles with improved solubility and target engagement under physiological conditions.
5-(Trifluoromethyl)-1H-imidazole-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and derivatization reactions. Its trifluoromethyl group enhances metabolic stability and modulates lipophilicity, while the carboxylic acid functionality facilitates amide bond formation, salt generation, or conjugation. The compound exhibits good bench stability and is compatible with common synthetic protocols, making it a practical choice for API development and structure-activity studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501
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Lot numbers can be found on the outside label of a product: