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Structure of 916210-02-1
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2-(Trifluoromethyl)isonicotinonitrile features a trifluoromethyl group and nitrile functionality positioned ortho to each other on an isonicotinonitrile scaffold. This electron-deficient heterocycle integrates readily into synthetic routes requiring strong π-accepting motifs, offering enhanced reactivity in cross-coupling and nucleophilic addition processes under standard conditions.
2-(Trifluoromethyl)isonicotinonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through nucleophilic substitution and transition-metal-catalyzed coupling reactions. Its trifluoromethyl and nitrile groups provide strong electron-withdrawing character, enhancing reactivity in C–H functionalization and facilitating access to bioactive molecules. The compound exhibits good bench stability and ease of purification, making it well-suited for scalable synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: