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Structure of 916454-59-6
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5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carbonitrile features a boronate ester group coupled with an electron-deficient thiophene core bearing a nitrile substituent. This combination enables efficient Suzuki-Miyaura coupling under mild conditions while maintaining bench-stable handling and enhanced solubility in polar organic solvents.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carbonitrile serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient coupling with aryl and heteroaryl halides under mild conditions, while the nitrile functionality provides orthogonal reactivity for downstream modifications. Bench-stable and readily purified by flash chromatography, it facilitates the construction of complex thiophene-based scaffolds common in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: