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Structure of 916792-15-9
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4-Bromo-5-fluoro-2-methylbenzonitrile features a trifunctional aromatic core with bromo, fluoro, and methyl groups positioned ortho to the nitrile. This electron-deficient scaffold enables direct coupling in cross-coupling reactions, offering high functional group tolerance and stability under standard conditions.
4-Bromo-5-fluoro-2-methylbenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted heterocycles via palladium-catalyzed cross-coupling. The ortho-methyl and nitrile groups provide complementary sites for functionalization, while the bromo and fluoro substituents offer high reactivity in Suzuki, Stille, and Buchwald-Hartwig reactions. Bench-stable and readily purified by recrystallization, it facilitates scalable access to complex aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: