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Structure of 917391-98-1
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This electron-deficient dihydropyridine aldehyde features a fluorinated ring system that enhances reactivity in nucleophilic addition and cycloaddition processes. The ortho-aldehyde group enables direct functionalization, while the conjugated carbonyl stabilizes reaction intermediates. Bench-stable under standard conditions, it serves as a key building block for bioactive heterocycles and synthetic intermediates in medicinal chemistry.
5-Fluoro-2-oxo-1,2-dihydropyridine-3-carbaldehyde serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyridine derivatives. Its conjugated enone-aldehyde functionality facilitates Michael additions, Mannich reactions, and condensation processes under mild conditions. The fluorine substituent enhances metabolic stability and modulates electronic properties, making it valuable for medicinal chemistry applications. Bench-stable and amenable to standard purification methods, it functions effectively in multistep syntheses requiring precise functional group placement.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: