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CS-W001157 4
Total: USD 88.00

6-Methylcoumarin

  • CAS No. 92-48-8

  • Cat. No. CS-0016827
  • Molecule weightNone
  • Purity≥98%
  • MDL No.MFCD00006875

*For research and further manufacturing use only, not for direct human use.

6-Methylcoumarin|CS-0016827

Structure of 92-48-8

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General Information

  • CAS No. 92-48-8
  • Cat. No. CS-0016827
  • Purity ≥98%
  • MDL No. MFCD00006875
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈O₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C1C=CC2=CC(C)=CC=C2O1

Description

Inhibiting NF-κB translocation and suppressing COX-2 expression, 6-Methylcoumarin (CAS 92-48-8) demonstrates potent anti-inflammatory effects in cellular models of chronic inflammation.

Application

6-Methylcoumarin (CAS 92-48-8) drives sustainable insecticide development by selectively targeting aphids while minimizing harm to pollinators, leveraging its natural bioactivity and defined mechanism of action. It also enhances analytical separations in conductive vial electromembrane extraction. Researchers exploit its signaling pathway modulation to stimulate melanogenesis via PKA/CREB, MAPK, AKT/PI3K, and GSK3β/β-catenin routes, revealing strong potential in dermatological and cosmetic applications.

Synthesis

  • Route1
    • null|null
      1310535-70-6
    • ~50%
    • In-stock
      6-Methylcoumarin|CS-0016827
      92-48-8

    References

    • Schmidt, Bernd; Krehl, Stefan Chemical Communications, 2011 , vol. 47, # 20 p. 5879 - 5881
  • Route2
    • In-stock
      NSC 97517|CS-W008835
      613-84-3
    • null|null
      4279-77-0
    • ~93%
    • In-stock
      6-Methylcoumarin|CS-0016827
      92-48-8

    References

    • Wei, Jia; Wang, Pengcheng; Jia, Qianfa; Huang, Jiaoyao; Du, Zhiyun; Zhang, Kun; Wang, Jian European Journal of Organic Chemistry, 2013 , # 21 p. 4499 - 4502
  • Route3
    • null|null
      110450-40-3
    • ~58%
    • In-stock
      6-Methylcoumarin|CS-0016827
      92-48-8

    References

    • Menon, Rajeev S.; Findlay, Alison D.; Bissember, Alex C.; Banwell, Martin G. Journal of Organic Chemistry, 2009 , vol. 74, # 22 p. 8901 - 8903

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317-H334
Precautionary Statements : P261-P264-P270-P272-P280-P284-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.21
  • LogP   2.10142
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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