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CS-W001157 4
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N1,N2-Bis(thiophen-2-ylmethyl)oxalamide

  • CAS No. 920366-91-2

  • Cat. No. CS-0079956
  • Molecule weight280.37
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N1,N2-Bis(thiophen-2-ylmethyl)oxalamide|CS-0079956

Structure of 920366-91-2

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General Information

  • CAS No. 920366-91-2
  • Cat. No. CS-0079956
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₂N₂O₂S₂
  • Molecular Weight 280.37
  • Synonym(s) N1,?N2-?bis(2-?thienylmethyl)?- Ethanediamide
  • SMILES O=C(NCC1=CC=CS1)C(NCC2=CC=CS2)=O

Description

N1,N2-Bis(thiophen-2-ylmethyl)oxalamide features a rigid oxalamide core flanked by thiophene-containing side chains, enabling strong π-stacking and directional molecular recognition. This architecture supports applications in supramolecular assembly and functional materials where electron-rich heterocycles enhance intermolecular interactions.

Application

N1,N2-Bis(thiophen-2-ylmethyl)oxalamide serves as a versatile bis-amide building block for the construction of heterocyclic scaffolds and peptide-like architectures. Its thiophene-functionalized side chains enable π-extended frameworks with enhanced electronic communication, while the oxalamide core offers robust stability and predictable hydrogen-bonding capacity. The compound facilitates efficient coupling reactions under standard conditions and exhibits excellent solubility and bench stability, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H372-H411
Precautionary Statements : P260-P264-P273-P391-P501

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Computational Chemistry Data

  • TPSA   58.2
  • LogP   1.7422
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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