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Structure of 920501-51-5
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6-Fluoro-2,3-dihydro-1H-indene-1-carboxylic acid features a fluorinated indene core with a carboxylic acid group at the 1-position, delivering enhanced metabolic stability and lipophilicity. This scaffold integrates readily into bioactive molecules, particularly in medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
6-Fluoro-2,3-dihydro-1H-indene-1-carboxylic acid serves as a valuable synthetic building block for medicinal chemistry and heterocyclic scaffold development. Its fluorinated indane core provides enhanced metabolic stability and modulated lipophilicity, while the carboxylic acid functionality enables straightforward derivatization via amide, ester, or acyl chloride formation. The compound exhibits good bench stability and facilitates efficient incorporation into complex molecular architectures through standard coupling reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: