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Structure of 923595-58-8
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5-Chloro-3-iodopyrazolo[1,5-a]pyrimidine features a fused heterocyclic core with complementary halogen handles: a chlorine at C5 and an iodine at C3. This arrangement enables selective cross-coupling reactions in late-stage functionalization, particularly in the synthesis of complex pyrazolopyrimidine-based pharmaceuticals and agrochemicals. The electron-deficient scaffold supports efficient palladium-catalyzed transformations under mild conditions.
5-Chloro-3-iodopyrazolo[1,5-a]pyrimidine serves as a versatile heterocyclic building block for late-stage functionalization in medicinal chemistry. The orthogonal reactivity of chlorine and iodine enables sequential cross-coupling transformations under palladium catalysis, facilitating the construction of complex pyrazolopyrimidine scaffolds. Bench-stable and compatible with standard purification methods, it functions reliably in Suzuki-Miyaura, Stille, and Buchwald-Hartwig reactions, supporting efficient diversification of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: