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Structure of 92381-17-4
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O-(4-(Trifluoromethyl)phenyl)hydroxylamine features a trifluoromethyl-substituted aryl ring that enhances electron-withdrawal and metabolic stability. This hydroxylamine derivative serves as a key intermediate in the synthesis of bioactive heterocycles, particularly in medicinal chemistry applications involving nitration or diazotization pathways.
O-(4-(Trifluoromethyl)phenyl)hydroxylamine serves as a versatile building block for the synthesis of trifluoromethyl-substituted heterocycles and pharmaceutical intermediates. Its stability under standard reaction conditions enables reliable use in nucleophilic substitution, coupling, and electrophilic aromatic substitution reactions. The trifluoromethyl group enhances metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. Functional group tolerance facilitates downstream derivatization without protection.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H227-H302-H312-H315-H318-H332-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: