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Structure of 92462-70-9
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5-(tert-Butyl)-1H-indole features a sterically hindered tert-butyl group at the 5-position of the indole core, enhancing stability and solubility in organic media. This substitution pattern imparts favorable electronic properties for use in pharmaceutical intermediates and functional materials synthesis under standard conditions.
5-(tert-Butyl)-1H-indole serves as a versatile building block in medicinal chemistry and materials science, offering enhanced solubility and steric bulk at the indole C5 position. Its stability under standard reaction conditions facilitates direct functionalization via electrophilic substitution or transition-metal-catalyzed coupling. The tert-butyl group provides excellent protection and orthogonality in multi-step syntheses, enabling efficient access to complex heterocyclic scaffolds and drug candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: