(R)-1-Boc-3-propylpiperazine

Name: (R)-1-Boc-3-propylpiperazine
Brand: ChemScene
Availability: InStock
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CAS No. 928025-57-4
Cat. No. CS-B0415
Purity≥97%
MDL No.MFCD07772107

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 928025-57-4

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Description

(R)-1-Boc-3-propyl-piperazine is a chiral piperazine derivative featuring a Boc-protected amine and a propyl substituent at the 3-position. This bench-stable, moisture-tolerant scaffold enables direct incorporation into complex molecular architectures. The stereochemistry at the piperazine nitrogen facilitates selective interactions in medicinal chemistry applications.

Application

(R)-1-Boc-3-propyl-piperazine serves as a versatile chiral building block in medicinal chemistry, enabling the construction of bioactive piperazine-containing scaffolds. Its Boc-protected amine offers excellent bench stability and compatibility with standard deprotection protocols, while the propyl chain provides favorable lipophilicity and conformational flexibility for target engagement. The molecule facilitates efficient functionalization at both nitrogen atoms and supports diverse coupling reactions in peptide and small-molecule synthesis.

General Information

CAS No. 928025-57-4
Cat. No. CS-B0415
Purity ≥97%
MDL No. MFCD07772107
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₂₄N₂O₂
Molecular Weight 228.34
Synonym(s) None
SMILES O=C(OC(C)(C)C)N1C[C@@H](CCC)NCC1

Computational Chemistry Data

TPSA 41.57
LogP 1.9954
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperazine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1-Boc-3-propylpiperazine

CAS No. 928025-57-4

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