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Structure of 929250-35-1
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6-(Benzyloxy)pyridine-3-boronic acid integrates a pyridine scaffold with a boronic acid and benzyloxy handle, enabling direct coupling in Suzuki-Miyaura reactions. The electron-deficient pyridine ring enhances reactivity, while the benzyl ether protects the hydroxyl during synthesis. This bench-stable derivative delivers efficient access to functionalized heterocycles under standard conditions.
6-(Benzyloxy)pyridine-3-boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. The pyridine scaffold provides strong coordination to transition metals, while the benzyloxy group offers orthogonal stability and convenient removal via acidolysis. Its boronic acid functionality enables reliable coupling with aryl and vinyl halides, facilitating access to complex heterocyclic architectures commonly found in pharmaceutical intermediates. Bench-stable and amenable to standard purification protocols, it functions effectively in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: