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CS-W001157 4
Total: USD 88.00

2-Methoxyphenylacetic acid

  • CAS No. 93-25-4

  • Cat. No. CS-D0984
  • Purity≥97%
  • MDL No.MFCD00004321
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Methoxyphenylacetic acid|CS-D0984

Structure of 93-25-4

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Description

2-Methoxyphenylacetic acid features a phenylacetic core with a methoxy group at the ortho position, delivering enhanced solubility and metabolic stability. This substitution pattern imparts favorable electronic and steric properties, enabling efficient integration into bioactive scaffolds and synthetic intermediates for pharmaceutical development under standard conditions.

Application

2-Methoxyphenylacetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-methoxy substituent enhances metabolic stability while maintaining compatibility with standard coupling reactions. The carboxylic acid group facilitates derivatization via amide, ester, or amidation protocols, offering reliable access to diverse scaffolds. Bench-stable and readily purified by recrystallization, it functions efficiently in multi-step syntheses requiring functional group tolerance and predictable reactivity.

General Information

  • CAS No. 93-25-4
  • Cat. No. CS-D0984
  • Purity ≥97%
  • MDL No. MFCD00004321
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₃
  • Molecular Weight 166.17
  • Synonym(s) 2-Methoxybenzeneacetic acid; o-methoxyphenylacetic acid; 2-Methoxyphenylacetic acid
  • SMILES COC1=CC=CC=C1CC(O)=O

Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.3223
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H318
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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