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Structure of 93-25-4
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2-Methoxyphenylacetic acid features a phenylacetic core with a methoxy group at the ortho position, delivering enhanced solubility and metabolic stability. This substitution pattern imparts favorable electronic and steric properties, enabling efficient integration into bioactive scaffolds and synthetic intermediates for pharmaceutical development under standard conditions.
2-Methoxyphenylacetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-methoxy substituent enhances metabolic stability while maintaining compatibility with standard coupling reactions. The carboxylic acid group facilitates derivatization via amide, ester, or amidation protocols, offering reliable access to diverse scaffolds. Bench-stable and readily purified by recrystallization, it functions efficiently in multi-step syntheses requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H318
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: