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CS-W001157 4
Total: USD 88.00

2,7-Dimethylquinoline

  • CAS No. 93-37-8

  • Cat. No. CS-0119502
  • Purity≥98%
  • MDL No.MFCD00006763

*For research and further manufacturing use only, not for direct human use.

2,7-Dimethylquinoline|CS-0119502

Structure of 93-37-8

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General Information

  • CAS No. 93-37-8
  • Cat. No. CS-0119502
  • Purity ≥98%
  • MDL No. MFCD00006763
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁N
  • Molecular Weight 157.21
  • Synonym(s) m-Toluquinaldine
  • SMILES CC1=CC=C2C=CC(C)=NC2=C1

Description

2,7-Dimethylquinoline is a sterically hindered quinoline derivative featuring methyl groups at the 2- and 7-positions, enhancing its electron-rich character and stability under standard conditions. This configuration imparts favorable solubility and reactivity profiles, making it a valuable scaffold in ligand design and organic synthesis.

Application

2,7-Dimethylquinoline serves as a versatile heterocyclic building block in medicinal chemistry and catalysis research. Its electron-rich core facilitates palladium-catalyzed cross-coupling reactions and functions effectively as a ligand in transition metal systems. The methyl groups at the 2- and 7-positions enhance bench stability and improve solubility in organic media, enabling straightforward purification and integration into complex molecular architectures.

Synthesis

  • Route1
    • null|null
      109-92-2
    • null|null
      108-44-1
    • ~91%
    • In-stock
      2,7-Dimethylquinoline|CS-0119502
      93-37-8

    References

    • Verma, Sanny; Verma, Deepak; Jain, Suman L. Tetrahedron Letters, 2014 , vol. 55, # 15 p. 2406 - 2409
  • Route2
    • null|null
      64-17-5
    • null|null
      108-44-1
    • ~89%
    • In-stock
      2,7-Dimethylquinoline|CS-0119502
      93-37-8

    References

    • Khusnutdinov; Bayguzina; Aminov Russian Chemical Bulletin, 2013 , vol. 62, # 1 p. 133 - 137 Izv. Akad. Nauk, Ser. Khim., 2013 , # 1 p. 134 - 138
  • Route3
    • null|null
      108-44-1
    • null|null
      123-73-9
    • ~%
    • In-stock
      2,7-Dimethylquinoline|CS-0119502
      93-37-8
    • 2,5-Dimethylquinoline|CS-0336135
      26190-82-9

    References

    • Spivey; Curd Journal of the Chemical Society, 1949 , p. 2656,2660 Full Text Show Details Utermohlen Journal of Organic Chemistry, 1943 , vol. 8, p. 544,546 Full Text Show Details Bowen et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4307,4310

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.85164
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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