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CS-W001157 4
Total: USD 88.00

3-Hydroxypicolinonitrile

  • CAS No. 932-35-4

  • Cat. No. CS-W011210
  • Purity≥98%
  • MDL No.MFCD01646135
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

3-Hydroxypicolinonitrile|CS-W011210

Structure of 932-35-4

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Description

3-Hydroxypicolinonitrile features a hydroxyl group flanked by a pyridine ring and a nitrile moiety, enabling dual functionality in synthetic transformations. This electron-deficient heterocycle integrates readily into complex scaffolds under mild conditions. The compound exhibits bench-stable handling characteristics and facilitates efficient derivatization in medicinal chemistry applications.

Application

3-Hydroxypicolinonitrile serves as a versatile building block in synthetic organic chemistry, enabling access to heterocyclic scaffolds through cyclization and functional group manipulation. Its ortho-hydroxy nitrile motif facilitates regioselective transformations, including ring closure to form quinoline and isoquinoline derivatives. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

General Information

  • CAS No. 932-35-4
  • Cat. No. CS-W011210
  • Purity ≥98%
  • MDL No. MFCD01646135
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄N₂O
  • Molecular Weight 120.11
  • Synonym(s) 3-hydroxypyridine-2-carbonitrile
  • SMILES OC1=CC=CN=C1C#N

Computational Chemistry Data

  • TPSA   56.91
  • LogP   0.65888
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 3439
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P302+P352-P304+P340

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