1-Bromo-5-fluoro-4-nitro-2-(trifluoromethyl)benzene

Name: 1-Bromo-5-fluoro-4-nitro-2-(trifluoromethyl)benzene
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 932374-77-1
Cat. No. CS-0636896
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Bromo-5-fluoro-4-nitro-2-(trifluoromethyl)benzene|CS-0636896

Structure of 932374-77-1

Size

Price

Quantity

* Please select Quantity before adding items.

Description

1-Bromo-5-fluoro-4-nitro-2-(trifluoromethyl)benzene features a highly electron-deficient aromatic core stabilized by strong inductive effects from the trifluoromethyl and nitro groups. This configuration enables efficient palladium-catalyzed cross-coupling reactions under mild conditions, with the bromo group serving as a reliable handle for C–C bond formation. The molecule exhibits excellent bench stability and compatibility with diverse reaction environments.

Application

1-Bromo-5-fluoro-4-nitro-2-(trifluoromethyl)benzene serves as a versatile building block for constructing complex fluorinated aromatic scaffolds. Its orthogonal reactivity enables palladium-catalyzed cross-coupling, nucleophilic substitution, and sequential functionalization. The trifluoromethyl and nitro groups enhance metabolic stability and modulate electronic properties, while the bromo and fluoro substituents provide distinct sites for further derivatization. Bench-stable and compatible with standard purification protocols, it facilitates efficient synthesis of advanced intermediates for pharmaceutical and agrochemical applications.

General Information

CAS No. 932374-77-1
Cat. No. CS-0636896
Purity ≥97%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₂BrF₄NO₂
Molecular Weight 287.99
Synonym(s) None
SMILES FC(C1=CC([N+]([O-])=O)=C(F)C=C1Br)(F)F

Computational Chemistry Data

TPSA 43.14
LogP 3.5152
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Nitro compounds

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

932374-77-1 sigma932374-77-1 manufacturer932374-77-1 price932374-77-1 structure932374-77-1 SDSbuy 932374-77-1932374-77-1 supplier932374-77-1 uses932374-77-1 molecular weightprice of 932374-77-1932374-77-1 chemical name formula of 932374-77-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-Bromo-5-fluoro-4-nitro-2-(trifluoromethyl)benzene

CAS No. 932374-77-1

Recommended Products