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Structure of 93249-44-6
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2-Fluoro-5-methylbenzaldehyde features a fluorine atom at the ortho position and a methyl group at the meta position relative to the aldehyde, creating a unique electronic profile. This electron-deficient aromatic scaffold enables selective coupling reactions in pharmaceutical synthesis, particularly in the construction of bioactive heterocycles. The aldehyde functionality provides a handle for nucleophilic addition and condensation chemistry under standard conditions.
2-Fluoro-5-methylbenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, heterocycles, and bioactive scaffolds. Its ortho-fluoro and meta-methyl groups provide enhanced metabolic stability and modulate electronic properties, while the aldehyde functionality facilitates imine formation, reductive amination, and coupling reactions. Bench-stable and readily purified by distillation or chromatography, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: