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Structure of 933-52-8
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Tetramethylcyclobutane-1,3-dione features two carbonyl groups flanked by methyl substituents on a strained cyclobutane ring, enhancing its reactivity in cycloaddition and condensation reactions. This electron-deficient scaffold serves as a robust building block for synthesizing complex heterocycles and natural product analogs under standard conditions.
Tetramethylcyclobutane-1,3-dione serves as a versatile synthon in organic synthesis, enabling efficient construction of substituted cyclohexane and pyran scaffolds via Diels-Alder reactions. Its enhanced stability and defined regiochemistry facilitate reliable heterocycle formation under mild conditions. The molecule’s four methyl groups provide steric protection and improve solubility, simplifying purification and enhancing compatibility with diverse functional groups in multi-step sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: