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Structure of 934020-34-5
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This morpholinomethyl-substituted trifluoromethyl benzoic acid features a polar, electron-rich morpholine ring linked via a methylene bridge to an electron-deficient aryl core. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid enables direct conjugation or derivatization in medicinal chemistry campaigns.
4-(Morpholinomethyl)-3-(trifluoromethyl)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amide and ester formation. The morpholinomethyl group offers enhanced solubility and metabolic stability, while the trifluoromethyl moiety imparts strong electron-withdrawing character and improved membrane permeability. Its bench-stable carboxylic acid functionality facilitates straightforward derivatization and purification, making it well-suited for high-throughput synthesis campaigns and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: