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CS-W001157 4
Total: USD 88.00

Tert-butyldiphenylsilanol

  • CAS No. 93547-88-7

  • Cat. No. CS-0458752
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Tert-butyldiphenylsilanol|CS-0458752

Structure of 93547-88-7

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Description

Tert-butyldiphenylsilanol offers a sterically shielded silanol group ideal for selective silylation reactions. The bulky tert-butyl and diphenyl substituents confer exceptional bench stability and moisture tolerance, enabling reliable handling under standard conditions. This reagent integrates seamlessly into synthetic workflows requiring protected silicon functionalities without unwanted side reactions.

Application

Tert-butyldiphenylsilanol serves as a stable, bench-friendly silyl protecting group reagent, enabling reliable protection of alcohols and carboxylic acids under mild conditions. Its steric bulk facilitates selective deprotection and enhances functional group tolerance in complex molecule synthesis. Widely used in medicinal chemistry and natural product synthesis, it functions effectively in nucleophilic substitution and coupling reactions, offering high stability during purification and storage.

General Information

  • CAS No. 93547-88-7
  • Cat. No. CS-0458752
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₀OSi
  • Molecular Weight 256.41
  • Synonym(s) Silanol, (1,1-dimethylethyl)diphenyl-
  • SMILES O[Si](C1=CC=CC=C1)(C2=CC=CC=C2)C(C)(C)C

Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.5387
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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