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Structure of 937366-54-6
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3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is a bench-stable boronate reagent featuring a planar indole core that enables efficient cross-coupling in palladium-catalyzed reactions. The tetramethyl-substituted dioxaborolane moiety enhances stability and solubility in polar organic solvents, facilitating reliable coupling with aryl and vinyl halides under standard conditions. This structure integrates seamlessly into complex molecular architectures, particularly in medicinal chemistry and materials synthesis.
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The dioxaborolane group enables stable, room-temperature handling and facilitates efficient C–C bond formation with aryl and heteroaryl halides. Its compatibility with diverse functional groups and straightforward purification make it ideal for constructing biaryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: