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CS-W001157 4
Total: USD 88.00

Chloromethyl morpholine-4-carboxylate

  • CAS No. 93765-68-5

  • Cat. No. CS-0160285
  • Purity≥97%
  • MDL No.MFCD20627473

*For research and further manufacturing use only, not for direct human use.

Chloromethyl morpholine-4-carboxylate|CS-0160285

Structure of 93765-68-5

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General Information

  • CAS No. 93765-68-5
  • Cat. No. CS-0160285
  • Purity ≥97%
  • MDL No. MFCD20627473
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀ClNO₃
  • Molecular Weight 179.60
  • Synonym(s) None
  • SMILES O=C(N1CCOCC1)OCCl

Description

Chloromethyl morpholine-4-carboxylate is a reactive electrophilic agent featuring a chloromethyl group tethered to a morpholine ring with a carboxylate at the 4-position. This configuration enables selective alkylation under mild conditions, particularly useful in peptide derivatization and bioconjugation workflows. The compound exhibits good stability and solubility in common organic solvents, facilitating efficient coupling reactions without requiring harsh activation.

Application

Chloromethyl morpholine-4-carboxylate serves as a versatile acylating agent and electrophilic building block in synthetic organic chemistry. Its chloromethyl group enables efficient alkylation of nucleophiles, while the morpholine-4-carboxylate moiety provides enhanced solubility and stability under standard reaction conditions. This compound facilitates the construction of heterocyclic scaffolds and functionalized intermediates with high regiocontrol, offering practical advantages in purification and scalability for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.77
  • LogP   0.6515
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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