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Structure of 94010-78-3
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This difluorinated acetic acid derivative features a sterically constrained aryl-fluoride motif, delivering enhanced metabolic stability and lipophilic character. The para-fluorophenyl group imparts electron-withdrawing effects, while the geminal difluoro substitution enhances both chemical robustness and membrane permeability. Designed for incorporation into bioactive scaffolds requiring precise electronic modulation and resistance to oxidative degradation.
2,2-Difluoro-2-(4-fluorophenyl)acetic acid serves as a stable, bench-ready building block for fluorinated aromatic motifs. Its difluoromethyl group enables direct incorporation into bioactive scaffolds via standard acylation and coupling reactions. The molecule exhibits excellent functional group tolerance and facilitates the synthesis of pharmaceutically relevant heterocycles and fluorinated ketones under mild conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: