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Structure of 940284-98-0
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2-(4-Boc-piperazino)pyrimidine-5-boronic acid pinacol ester delivers a stable, bench-ready boronate handle for palladium-catalyzed cross-coupling. The Boc-protected piperazine moiety enhances solubility and functional group tolerance, enabling seamless integration into complex heterocyclic architectures under standard conditions.
2-(4-Boc-piperazino)pyrimidine-5-boronic acid pinacol ester serves as a versatile building block for constructing pyrimidine-based scaffolds in medicinal chemistry. Its boronic ester functionality enables reliable Suzuki-Miyaura cross-coupling reactions under mild conditions, while the Boc-protected piperazine offers orthogonal reactivity for downstream derivatization. The compound exhibits excellent bench stability and simplifies purification, making it well-suited for iterative synthesis campaigns targeting kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: