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Structure of 940890-90-4
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(S)-tert-Butyl 3-(methylsulfonyloxy)piperidine-1-carboxylate is a bench-stable, moisture-tolerant chiral building block featuring a piperidine core with a strategically positioned methylsulfonyloxy leaving group. This configuration enables efficient late-stage functionalization in asymmetric synthesis, particularly in palladium-catalyzed cross-coupling reactions where controlled reactivity and stereochemical integrity are paramount.
(S)-tert-Butyl 3-(methylsulfonyloxy)piperidine-1-carboxylate serves as a versatile chiral building block for asymmetric synthesis, enabling efficient introduction of piperidine scaffolds via nucleophilic displacement. The methylsulfonyloxy group provides excellent leaving group capability under mild conditions, facilitating C–N and C–C bond formations with high stereoretention. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for medicinal chemistry campaigns requiring stereocontrolled heterocycle construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: