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Structure of 942199-56-6
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2-Chloro-5-cyanobenzene-1-sulfonyl chloride features a strategically positioned sulfonyl chloride group flanked by electron-withdrawing chlorine and cyano substituents, enabling selective conjugate addition reactions. This combination enhances electrophilicity while maintaining stability under standard bench conditions. The molecule integrates readily into complex heterocyclic scaffolds and serves as a key intermediate in the synthesis of functionalized aromatic systems for pharmaceutical and agrochemical applications.
2-Chloro-5-cyanobenzene-1-sulfonyl chloride serves as a versatile building block for sulfonamide-based scaffolds in medicinal chemistry. Its reactivity enables efficient coupling with amines under mild conditions, facilitating rapid access to functionalized aryl sulfonamides. The molecule exhibits good bench stability and tolerates common functional groups, supporting its use in multi-step syntheses and API development workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: