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Structure of 943-15-7
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4-Isopropyl-1-methyl-2-nitrobenzene features a nitro group at the para position relative to the isopropyl substituent, enhancing electron withdrawal and directing electrophilic substitution. The methyl and isopropyl groups provide steric bulk and solubility in organic media. This compound serves as a key intermediate in synthesizing functionalized aromatic systems for pharmaceutical and agrochemical applications.
4-Isopropyl-1-methyl-2-nitrobenzene serves as a versatile aromatic building block in medicinal chemistry, enabling direct functionalization at the nitro group for subsequent reduction to an amine or coupling reactions. Its ortho-substituted nitro and methyl groups provide steric and electronic modulation, enhancing regioselectivity in downstream transformations. The isopropyl moiety contributes favorable lipophilicity and metabolic stability, making it a practical scaffold for API development. Bench-stable and compatible with standard synthetic workflows, it facilitates efficient access to complex heterocyclic systems and drug candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: