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Structure of 943726-01-0
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Propargyl-PEG2-MS features a reactive maleimide group flanked by a short PEG spacer and a terminal alkyne, enabling site-specific bioconjugation via copper-catalyzed azide-alkyne cycloaddition or strain-promoted variants. This bifunctional linker combines aqueous solubility with orthogonal reactivity, streamlining the integration of biomolecules into functionalized surfaces or delivery systems.
Propargyl-PEG2-MS serves as a versatile bifunctional linker for bioconjugation and polymer chemistry. The propargyl group enables reliable copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the maleimide moiety selectively reacts with thiols under physiological conditions. This combination facilitates efficient, site-specific conjugation in peptide, protein, and oligonucleotide modifications, with PEG2 providing enhanced solubility and reduced non-specific binding.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: