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Structure of 946681-88-5
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5-Bromo-4,6-difluoropyrimidine serves as a key heterocyclic building block in medicinal chemistry and agrochemical synthesis. The strategically positioned bromo and difluoro substituents enable efficient cross-coupling reactions and enhance metabolic stability. This electron-deficient pyrimidine core integrates readily into bioactive scaffolds under standard conditions.
5-Bromo-4,6-difluoropyrimidine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling site-selective functionalization via palladium-catalyzed cross-coupling. The bromo group facilitates Suzuki, Stille, and Negishi reactions, while the difluoro substitution enhances metabolic stability and modulates electronic properties. Its bench-stable crystalline form simplifies handling and purification, making it ideal for iterative library construction and process-scale applications.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: