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Methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoate

  • CAS No. 94790-24-6

  • Cat. No. CS-0133105
  • Purity≥98%
  • MDL No.MFCD03788050

*For research and further manufacturing use only, not for direct human use.

Methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoate|CS-0133105

Structure of 94790-24-6

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General Information

  • CAS No. 94790-24-6
  • Cat. No. CS-0133105
  • Purity ≥98%
  • MDL No. MFCD03788050
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₃NO₅
  • Molecular Weight 309.36
  • Synonym(s) O-methyl-N-tert-butoxycarbonyl-L-tyrosine methyl ester
  • SMILES O=C(OC)[C@H](CC1=CC=C(OC)C=C1)NC(OC(C)(C)C)=O

Description

Methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoate features a chiral α-amino acid scaffold with a protected amine and a para-methoxyaryl side chain. This bench-stable building block integrates readily into peptide synthesis workflows, enabling efficient access to bioactive analogs through selective deprotection and coupling strategies.

Application

Methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoate serves as a key chiral building block for synthesizing pharmaceutically relevant β-arylethylamine derivatives. The protected amino group enables orthogonal deprotection, while the ester functionality supports versatile transformations. Its bench-stable nature and compatibility with standard coupling and reduction protocols facilitate efficient access to bioactive scaffolds in medicinal chemistry campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Computational Chemistry Data

  • TPSA   73.86
  • LogP   2.304
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   5

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