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Structure of 95104-21-5
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2-Chloroquinoline-3-carbonitrile features a fused heterocyclic core with complementary electron-withdrawing groups: a chlorine at the 2-position and a nitrile at the 3-position. This combination imparts enhanced reactivity in cross-coupling processes and facilitates incorporation into pharmaceutical scaffolds requiring halogenated, electron-deficient platforms. The compound exhibits bench-stable handling characteristics and solubility in common organic solvents.
2-Chloroquinoline-3-carbonitrile serves as a versatile building block in medicinal chemistry and materials science, enabling efficient construction of quinoline-based scaffolds. Its ortho-chloro and nitrile groups facilitate diverse transformations, including palladium-catalyzed cross-couplings and nucleophilic substitutions, with excellent bench stability and straightforward purification.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H318
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Precautionary Statements : P264-P270-P280-P330-P405-P501
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Lot numbers can be found on the outside label of a product: