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Structure of 951625-93-7
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Methyl 4-chloro-7-azaindole-5-carboxylate features a sterically hindered, electron-deficient azaindole core paired with a reactive ester handle. This combination enables direct coupling in late-stage functionalization workflows. The molecule exhibits enhanced stability under standard conditions and facilitates efficient incorporation into complex heterocyclic architectures.
Methyl 4-chloro-7-azaindole-5-carboxylate serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the C4 position via palladium-catalyzed cross-coupling reactions. Its chloro group exhibits high reactivity in Suzuki, Stille, and Negishi transformations, while the methyl ester facilitates downstream derivatization. The 7-azaindole core provides enhanced solubility and metabolic stability, making it valuable for medicinal chemistry applications. Bench-stable and amenable to standard purification methods, it functions efficiently in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: