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Structure of 953039-66-2
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7-Bromo-2-chloroquinazoline is a halogenated quinazoline scaffold featuring complementary reactivity at the 7-bromo and 2-chloro positions. This electron-deficient heterocycle enables direct functionalization in cross-coupling reactions, serving as a key intermediate in medicinal chemistry for kinase inhibitor development. The molecule exhibits high stability under standard conditions and facilitates modular diversification through orthogonal substitution pathways.
7-Bromo-2-chloroquinazoline serves as a versatile building block for the synthesis of quinazoline-based pharmaceuticals and functional materials. The molecule features orthogonal halogen handles—bromine at C7 and chlorine at C2—that enable selective cross-coupling reactions under palladium catalysis. Its bench-stable crystalline form facilitates handling and purification, while its compatibility with diverse reaction conditions supports efficient access to complex heterocyclic scaffolds in medicinal chemistry and materials science workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: