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CS-W001157 4
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(3-Chloro-5-(methoxycarbonyl)phenyl)boronic acid

  • CAS No. 957120-26-2

  • Cat. No. CS-0099814
  • Purity≥97%
  • MDL No.MFCD09475906
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

(3-Chloro-5-(methoxycarbonyl)phenyl)boronic acid|CS-0099814

Structure of 957120-26-2

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Description

This boronic acid features a chlorinated aryl ring paired with a methoxycarbonyl group, enabling selective coupling in Suzuki-Miyaura reactions. The ortho-chlorine facilitates downstream functionalization, while the boronic moiety offers high reactivity and bench-stable handling under standard conditions.

Application

(3-Chloro-5-(methoxycarbonyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The chloro and methoxycarbonyl groups provide orthogonal reactivity for downstream functionalization, while the boronic acid moiety offers excellent bench stability and compatibility with standard aqueous workups. Its predictable coupling behavior and ease of purification make it ideal for medicinal chemistry and process development workflows.

General Information

  • CAS No. 957120-26-2
  • Cat. No. CS-0099814
  • Purity ≥97%
  • MDL No. MFCD09475906
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BClO₄
  • Molecular Weight 214.41
  • Synonym(s) Methyl 3-borono-5-chlorobenzoate
  • SMILES OB(O)C1=CC(Cl)=CC(C(OC)=O)=C1

Computational Chemistry Data

  • TPSA   66.76
  • LogP   -0.1936
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

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