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Structure of 957121-07-2
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This boronic acid features a strategically positioned hydroxyl group flanked by chlorine and fluorine substituents, enabling enhanced reactivity in Suzuki-Miyaura coupling. The electron-withdrawing halogens stabilize the boronate moiety while improving solubility in polar solvents. This combination facilitates efficient cross-coupling under mild conditions, making it well-suited for synthesizing complex arylated scaffolds in medicinal chemistry and materials science.
(2-Chloro-6-fluoro-3-hydroxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-chloro and fluoro substituents provide enhanced reactivity and positional control in downstream functionalization, while the boronic acid group offers excellent bench stability and compatibility with diverse reaction media. Its utility is further reinforced by high functional group tolerance and straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: