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Structure of 958451-91-7
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This boronate moiety features a trifluoromethyl-substituted thiophene scaffold, delivering enhanced stability and electron-withdrawing character. The pendant boronic acid group enables efficient Suzuki-Miyaura cross-coupling under standard conditions, facilitating the construction of complex heteroaromatic architectures with high functional group tolerance.
(5-(Trifluoromethyl)thiophen-2-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its trifluoromethylthiophene moiety imparts enhanced metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. The boronic acid group exhibits excellent bench stability, tolerates a range of functional groups, and facilitates straightforward purification, supporting scalable synthesis and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: