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Structure of 958646-70-3
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2-Chloro-6-hydroxyphenylboronic acid features a hydroxyl group flanked by a chlorinated aryl ring and a boronic acid moiety, enabling direct coupling in Suzuki-Miyaura reactions. The ortho-hydroxy arrangement promotes chelation-assisted activation, enhancing reaction efficiency under mild conditions. This bench-stable derivative integrates readily into complex molecular architectures with minimal purification overhead.
2-Chloro-6-hydroxyphenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The ortho-chloro and phenolic hydroxyl groups provide orthogonal reactivity for sequential functionalization, while the boronic acid moiety offers good bench stability and compatibility with standard coupling conditions. Its utility is enhanced by straightforward purification and predictable regioselectivity in transition-metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: