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Structure of 95970-22-2
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1,2-Dibromo-3-methoxybenzene features a methoxy group positioned ortho to two bromine substituents, creating a uniquely activated aromatic scaffold. This configuration enables selective cross-coupling reactions under palladium catalysis, where the electron-donating methoxy group stabilizes intermediates and directs regioselective functionalization. The compound exhibits bench-stable handling characteristics and integrates efficiently into complex molecular architectures requiring dual halogenation sites.
1,2-Dibromo-3-methoxybenzene serves as a versatile ortho-dibrominated aromatic building block for palladium-catalyzed cross-coupling reactions. The methoxy group provides moderate electron donation and enhances solubility, while the bromine atoms enable sequential functionalization under standard Suzuki, Stille, or Negishi conditions. Bench-stable and readily purified by column chromatography, it functions reliably in the synthesis of complex biaryl architectures and substituted heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335-H413
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Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: