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CS-W001157 4
Total: USD 88.00

5-Difluoromethoxy-2-mercaptobenzimidazole

  • CAS No. 97963-62-7

  • Cat. No. CS-W021039
  • Purity≥98%
  • MDL No.MFCD00467504
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Difluoromethoxy-2-mercaptobenzimidazole|CS-W021039

Structure of 97963-62-7

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Description

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole may be used in the synthesis of pantoprazole, a drug for treating gastroesophageal reflux disease and gastrointestinal disorders.

Application

5-Difluoromethoxy-2-mercaptobenzimidazole serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds through palladium-catalyzed cross-coupling and electrophilic substitution reactions. The difluoromethoxy group enhances metabolic stability and modulates lipophilicity, while the thiol functionality facilitates conjugation and coordination chemistry. Bench-stable and compatible with standard purification methods, it functions effectively in multi-step syntheses requiring functional group tolerance and structural diversity.

General Information

  • CAS No. 97963-62-7
  • Cat. No. CS-W021039
  • Purity ≥98%
  • MDL No. MFCD00467504
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆F₂N₂OS
  • Molecular Weight None
  • Synonym(s) None
  • SMILES S=C1NC2=CC(OC(F)F)=CC=C2N1

Computational Chemistry Data

  • TPSA   40.81
  • LogP   2.82689
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H413
Precautionary Statements : P273-P501

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